Boucrot, E;
Kirchhausen, T;
(2008)
Mammalian cells change volume during mitosis.
PLOS One
, 3
(1)
, Article e1477. 10.1371/journal.pone.0001477.
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Abstract
Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery observed in mitotic cells [1].
| Type: | Article |
|---|---|
| Title: | Mammalian cells change volume during mitosis. |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pone.0001477 |
| Publisher version: | http://dx.doi.org/10.1371/journal.pone.0001477 |
| Language: | English |
| Additional information: | © 2008 Boucrot, Kirchhausen. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Supported by NIH GM075252 and GM62566 (TK). EB was supported by a fellowship from the International Human Frontier Science Program Organization (HFSPO). |
| Keywords: | Animals, Cell Cycle, Cell Line, Cell Size, Fluorescence, Haplorhini, Mitosis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1322433 |
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