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The use of clostridium botulinum toxin in palatal myclonus. A preliminary report

Saeed, SR; Brookes, GB; (1993) The use of clostridium botulinum toxin in palatal myclonus. A preliminary report. Journal of Laryngology and Otology , 107 (3) 208 - 210. 10.1017/S0022215100122650. Green open access

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Abstract

Palatal myoclonus is a rare syndrome characterized by involuntary rhythmical movements of the soft palate giving rise to clicking objective tinnitus. The intrusive nature of the tinnitus prompts patients to seek medical advice but to date no single treatment modality has been shown to be consistently effective. We present three cases in whom various management regimes were unsuccessful and in whom botulinum toxin injection to the palatal muscles was undertaken. All three cases were rendered free of their tinnitus with complete abolition of the myoclonus. The questions of optimum dosage as well as frequency of injection will be answered as greater numbers are treated by this method.

Type: Article
Title: The use of clostridium botulinum toxin in palatal myclonus. A preliminary report
Open access status: An open access version is available from UCL Discovery
DOI: 10.1017/S0022215100122650
Publisher version: http://dx.doi.org/10.1017/S0022215100122650
Language: English
Additional information: Copyright Cambridge University Press 1993
Keywords: Clostridium botulinum, Myoclonus, Palatal
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > The Ear Institute
URI: https://discovery.ucl.ac.uk/id/eprint/1320829
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