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Actinomycosis of the sigmoid colon: A case report

Privitera, A; Milkhu, CS; Datta, V; Rodriguez-Justo, M; Windsor, A; Cohen, CR; (2009) Actinomycosis of the sigmoid colon: A case report. World Journal of Gastrointestinal Surgery , 1 (1) 62 - 64. 10.4240/wjgs.v1.i1.62. Green open access

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Abstract

Abdominal actinomycosis is a chronic suppurative infection caused by Actinomyces species. The ileo-cecal region is most commonly affected, while the left side of the colon is more rarely involved. The infection has a tendency to infiltrate adjacent tissues and is therefore rarely confined to a single organ. Presentation may vary from non specific symptoms and signs to an acute abdomen. A computed tomography scan is helpful in identifying the inflammatory process and the organs involved. It also allows visual guidance for percutaneous drainage of abscesses, thus aiding diagnosis. Culture is difficult because of the anaerobic character and slow growth of actinomycetes. Colonoscopy is usually normal, but may shows signs of external compression. Preoperative diagnosis is rare and is established only in less than 10% of cases. In uncomplicated disease, high dose antibiotic therapy is the mainstay of treatment. Surgery is often performed because of a difficulty in diagnosis. Surgery and antibiotics are required in the case of complicated disease. Combined medical and surgical treatment achieves a cure in about 90% of cases. The authors report a case of sigmoid actinomycosis where diagnosis was made from the histology, and a review of the literature is presented.

Type: Article
Title: Actinomycosis of the sigmoid colon: A case report
Location: China
Open access status: An open access version is available from UCL Discovery
DOI: 10.4240/wjgs.v1.i1.62
Publisher version: http://dx.doi.org/10.4240/wjgs.v1.i1.62
Language: English
Additional information: © Baishideng Publishing Group Co., Limited. Published under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license (CC BY-NC). PMCID: PMC2999117
Keywords: Abdominal pain, Actinomycosis, Gram-positive bacteria, Sigmoid colon, Sulfur
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Pathology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
URI: https://discovery.ucl.ac.uk/id/eprint/1312964
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