Ariyaratnam, R;
Casas, JP;
Whittaker, J;
Smeeth, L;
Hingorani, AD;
Sharma, P;
(2007)
Genetics of ischaemic stroke among persons of non-European descent: A meta-analysis of eight genes involving; 32,500 individuals.
PLoS Medicine
, 4
(4)
, Article e131. 10.1371/journal.pmed.0040131.
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Abstract
Ischaemic stroke in persons of European descent has a genetic basis, but whether the stroke-susceptibility alleles, the strength of any association, and the extent of their attributable risks are the same in persons of non-European descent remains unanswered. Whether ethnicity itself has a relevant or substantial contribution on those effect estimates is controversial. Comparative analyses between the ethnic groups may allow general conclusions to be drawn about polygenic disorders.
| Type: | Article |
|---|---|
| Title: | Genetics of ischaemic stroke among persons of non-European descent: A meta-analysis of eight genes involving; 32,500 individuals |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pmed.0040131 |
| Publisher version: | http://dx.doi.org/10.1371/journal.pmed.0040131 |
| Language: | English |
| Additional information: | © 2007 Ariyaratnam et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics |
| URI: | https://discovery.ucl.ac.uk/id/eprint/120330 |
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