UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Converging language streams in the human temporal lobe

Spitsyna, G; Warren, JE; Scott, SK; Turkheimer, FE; Wise, RJS; (2006) Converging language streams in the human temporal lobe. J NEUROSCI , 26 (28) 7328 - 7336. 10.1523/JNEUROSCI.0559-06.2006. Green open access

[img]
Preview
PDF
10350.pdf

Download (489kB)

Abstract

There is general agreement that, after initial processing in unimodal sensory cortex, the processing pathways for spoken and written language converge to access verbal meaning. However, the existing literature provides conflicting accounts of the cortical location of this convergence. Most aphasic stroke studies localize verbal comprehension to posterior temporal and inferior parietal cortex (Wernicke's area), whereas evidence from focal cortical neurodegenerative syndromes instead implicates anterior temporal cortex. Previous functional imaging studies in normal subjects have failed to reconcile these opposing positions. Using a functional imaging paradigm in normal subjects that used spoken and written narratives and multiple baselines, we demonstrated common activation during implicit comprehension of spoken and written language in inferior and lateral regions of the left anterior temporal cortex and at the junction of temporal, occipital, and parietal cortex. These results indicate that verbal comprehension uses unimodal processing streams that converge in both anterior and posterior heteromodal cortical regions in the left temporal lobe.

Type: Article
Title: Converging language streams in the human temporal lobe
Open access status: An open access version is available from UCL Discovery
DOI: 10.1523/JNEUROSCI.0559-06.2006
Keywords: speech, reading, PET, temporal pole, fusiform gyrus, temporoparietal cortex, TRANSCORTICAL SENSORY APHASIA, CONSCIOUS RESTING STATE, SEMANTIC DEMENTIA, HUMAN BRAIN, INFEROTEMPORAL CORTEX, SPEECH-PERCEPTION, WORD RECOGNITION, AUDITORY-SYSTEM, FUNCTIONAL MRI, BASE-LINE
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Institute of Cognitive Neuroscience
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Language and Cognition
URI: https://discovery.ucl.ac.uk/id/eprint/10350
Downloads since deposit
301Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item