Deacon, L;
Pankhurst, L;
Liu, J;
Drew, GH;
Hayes, ET;
Jackson, S;
Longhurst, J;
... Tyrrel, S; + view all
(2009)
Endotoxin emissions from commercial composting activities.
Environmental Health
, 8
(Suppl )
, Article S9. 10.1186/1476-069X-8-S1-S9.
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Abstract
This paper describes an exploratory study of endotoxin emissions and dispersal from a commercial composting facility. Replicated samples of air were taken by filtration at different locations around the facility on 10 occasions. Measurements were made of endotoxin and associated culturable microorganisms. The inflammatory response of cell cultures exposed to extracts from the filters was measured. Endotoxin was detected in elevated concentrations close to composting activities. A secondary peak, of lesser magnitude than the peak at source was detected at 100-150 m downwind of the site boundary. Unexpectedly high concentrations of endotoxin were measured at the most distant downwind sampling point. Extracted endotoxin was found to stimulate human monocytes and a human lung epithelial cell line to produce significant amounts of pro-inflammatory cytokines. On a weight basis, endotoxin extracted from the composting source has a greater inflammatory cytokine inducing effect than commercial E. coli endotoxin.
| Type: | Article |
|---|---|
| Title: | Endotoxin emissions from commercial composting activities |
| Event: | Joint Environment and Human Health Programme/Annual Science Day Conference and Workshop |
| Location: | Birmingham, ENGLAND |
| Dates: | 2009-02-24 - 2009-02-25 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1476-069X-8-S1-S9 |
| Publisher version: | http://dx.doi.org/10.1186/1476-069X-8-S1-S9 |
| Language: | English |
| Additional information: | © 2009 Deacon et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Swine confinement buildings, Exposure assessment, Health, Facilities, Air, Assessments, Workers, Dust |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/102423 |
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