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Proactive Cognitive Stimulation for Younger Adults With Down Syndrome. A Feasibility Randomised Control Trial

Hardiman, Sharon; Cousins, Rory; Ryan, Aisling; Kennedy, Maria; Hagan, Leigh; Santos, Flavia H; (2025) Proactive Cognitive Stimulation for Younger Adults With Down Syndrome. A Feasibility Randomised Control Trial. Journal of Applied Research in Intellectual Disabilities , 38 (5) , Article e70120. 10.1111/jar.70120. Green open access

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Abstract

Background: Most adults with Down syndrome develop Alzheimer's disease (AD) pathology in their 30s, yet research into cognitive health programmes for this group remains limited. / / Method: A mixed-methods feasibility randomised control trial (RCT) evaluated an adapted, manualised group-based cognitive stimulation therapy (CST) programme for adults with Down syndrome (N = 12; Mage = 30) without dementia. Participants were randomly assigned to CST (n = 6) or control (services as usual; n = 6), with assessments at baseline, post-programme, and four-month follow-up by a blinded researcher. / / Results: The adapted CST was feasible, with high attendance, strong satisfaction, and good CST programme fidelity (all > 85%). CST participants showed significant gains in adaptive behaviour at post-programme, maintained at follow-up, and a trend towards improved episodic memory at post-programme. / / Conclusion: Manualised group-based CST can be successfully adapted for younger adults with Down syndrome and shows promise in supporting cognitive health for this population.

Type: Article
Title: Proactive Cognitive Stimulation for Younger Adults With Down Syndrome. A Feasibility Randomised Control Trial
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/jar.70120
Publisher version: https://doi.org/10.1111/jar.70120
Language: English
Additional information: This version is the author accepted manuscript. For the purpose of open access, the author(s) has applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising from this submission
Keywords: cognitive health, cognitive stimulation therapy, down syndrome, feasibility RCT, healthy ageing
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Psychology and Human Development
URI: https://discovery.ucl.ac.uk/id/eprint/10218987
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