Kezdi, Árpád;
Horvath, Viktor József;
Hangacs, Regina;
Tabak, Ádám Gyula;
Fogarasi, Dominic Joseph;
Vadon, Dániel;
Grosz, György;
... Nagy, Anikó; + view all
(2025)
Effects of Physical Activity, Metabolic Syndrome, and Social Status on ECG Parameters in Children: A Prospective Cohort Study.
Journal of Cardiovascular Development and Disease
, 12
(10)
, Article 385. 10.3390/jcdd12100385.
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Abstract
(1) Background: Physical activity, altered metabolic parameters, and socio-economic status may affect electrocardiographic (ECG) parameters in children. However, a direct comparison of their effects on resting ECG has not yet been performed. (2) Methods: A total of 139 participants (60 male), aged 10–17 years, were recruited. Resting 1-minute ECG recordings and clinical and laboratory investigations were obtained, while socio-economic status and physical activity were assessed using a questionnaire. Associations between these factors and ECG parameters were analyzed using analysis of covariance (ANCOVA). (3) Results: Age, sex, metabolic syndrome, and physical activity significantly influenced the average RR interval (η2 = 0.292, 0.070, 0.078, and 0.070, respectively). Similar effects were observed on the T_end–P interval. The PR, QRS, QTc, and T_peak–T_end intervals were moderately influenced by age (η2 = 0.084, 0.056, 0.072, and 0.049, respectively). QTc was additionally affected by sex (η2 = 0.060). None of the modifiable factors had any effect on depolarization or repolarization parameters. Socio-economic status had no significant effect on resting ECG. (4) Conclusions: Physical activity exerts similar effects on resting ECG in both sexes, while metabolic syndrome is an independent determinant of several ECG parameters. Further studies are warranted to clarify the clinical relevance of these findings.
| Type: | Article |
|---|---|
| Title: | Effects of Physical Activity, Metabolic Syndrome, and Social Status on ECG Parameters in Children: A Prospective Cohort Study |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3390/jcdd12100385 |
| Publisher version: | https://doi.org/10.3390/jcdd12100385 |
| Language: | English |
| Additional information: | Copyright © 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Children; resting ECG; metabolic syndromre; sport activity; social status |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10217377 |
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