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Replication of blood DNA methylomic signatures associated with cerebrospinal fluid levels of YKL-40 and NfL biomarkers

Kaleck, Timo; Campos-Martin, Rafael; Cano, Amanda; Fernández, Maria V; Martino-Adami, Pamela; Kleineidam, Luca; Fuentes, Victor MA; ... Ramirez, Alfredo; + view all (2025) Replication of blood DNA methylomic signatures associated with cerebrospinal fluid levels of YKL-40 and NfL biomarkers. Alzheimer's & Dementia , 21 (9) , Article e70647. 10.1002/alz.70647. Green open access

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Type: Article
Title: Replication of blood DNA methylomic signatures associated with cerebrospinal fluid levels of YKL-40 and NfL biomarkers
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/alz.70647
Publisher version: https://doi.org/10.1002/alz.70647
Language: English
Additional information: © 2025 The Author(s). This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. Alzheimer’s & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer’s Association.
Keywords: Alzheimer's disease (AD), DNA methylation, YKL‐40, amyloid, biomarker, blood, cerebrospinal fluid (CSF), epigenetics, epigenome‐wide association study (EWAS), neurofilament light (NfL), ptau, replication
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Institute of Cognitive Neuroscience
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People
URI: https://discovery.ucl.ac.uk/id/eprint/10216925
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