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Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document

Rajasekharan, S; Lygidakis, N; Cauwels, R; Declerck, D; Monteiro, J; Parekh, S; (2025) Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document. European Archives of Paediatric Dentistry 10.1007/s40368-025-01068-9. (In press). Green open access

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Abstract

Purpose: The European Academy of Paediatric Dentistry (EAPD) has developed this best clinical practice guidance on the use of antibiotics in pediatric dentistry, aiming to address challenges posed by antimicrobial resistance (AMR) and promote the responsible use of antibiotics. // Methods: A comprehensive review of existing literature and global policies was conducted to evaluate antibiotic-prescribing practices for children. Recommendations were developed through a consensus process involving experts in pediatric dentistry during the EAPD policy workshop in Prague in May 2023. // Results: The guidelines highlight the critical role of prudent antibiotic use to mitigate the growing threat of AMR. Specific recommendations include no routine antibiotic use for localized pulpitis or abscess without systemic involvement and targeted use for odontogenic infections with systemic signs. Detailed dosage protocols are provided, accounting for age, weight, and clinical context. Prophylaxis is recommended only for high-risk patients undergoing specific invasive procedures. Significant variations in national practices were noted, underlining the need for harmonized evidence-based protocols. // Conclusion: These guidelines serve as a framework to optimize antibiotic use in children, emphasizing the importance of targeted prescribing practices and the implementation of preventive strategies in pediatric dental care.

Type: Article
Title: Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s40368-025-01068-9
Publisher version: https://doi.org/10.1007/s40368-025-01068-9
Language: English
Additional information: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: Antibiotics; Prophylaxis; Antimicrobial resistance
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > EDI Craniofacial and Development Sci
URI: https://discovery.ucl.ac.uk/id/eprint/10215677
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