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British Society of Gastroenterology guidelines on inflammatory bowel disease in adults: 2025

Moran, Gordon W; Gordon, Morris; Sinopolou, Vassiliki; Radford, Shellie J; Darie, Ana-Maria; Vuyyuru, Sudheer Kumar; Alrubaiy, Laith; ... IBD guideline development group, .; + view all (2025) British Society of Gastroenterology guidelines on inflammatory bowel disease in adults: 2025. Gut , 74 (Suppl 2) s1-s101. 10.1136/gutjnl-2024-334395. Green open access

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Abstract

In response to recent advancements in inflammatory bowel disease (IBD) management, the British Society of Gastroenterology (BSG) Clinical Services and Standards Committee (CSSC) has commissioned the BSG IBD section to update its guidelines, last revised in 2019. These updated guidelines aim to complement the IBD standards and promote the use of the national primary care diagnostic pathway for lower gastrointestinal symptoms to enhance diagnostic accuracy and timeliness. Formulated through a systematic and transparent process, this document reflects a consensus of best practices based on current evidence. The guideline, while developed primarily for the UK, is structured to support IBD management internationally. It is endorsed by the BSG executive board and CSSC without external commercial funding, with involvement primarily supported through professional roles in public institutions and the National Health Service (NHS). Methodological revisions since the prior guidelines have enhanced rigor in technical review and development, with methodology details published independently following peer review. In developing the recommendations, 89 clinical experts and stakeholders participated in an online survey, identifying primary outcomes, such as clinical and endoscopic remission, as well as adverse event metrics, all stratified by clinically relevant effect sizes. These guidelines are intended to support clinical decision-making but are not prescriptive, recognizing that individual clinical scenarios may warrant tailored approaches. Further research may inform future revisions as new evidence emerges.

Type: Article
Title: British Society of Gastroenterology guidelines on inflammatory bowel disease in adults: 2025
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/gutjnl-2024-334395
Publisher version: https://doi.org/10.1136/gutjnl-2024-334395
Language: English
Additional information: © The Author(s), 2025. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Keywords: Crohn's Disease, IBD, Inflammatory Bowel Disease, Infliximab, Ulcerative Colitis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI: https://discovery.ucl.ac.uk/id/eprint/10210552
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