Beta papillomaviruses: From foe to friend in skin cancer immunity

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Beta papillomaviruses: From foe to friend in skin cancer immunity

Lebrusant-Fernandez, Marta; Reading, James L; (2025) Beta papillomaviruses: From foe to friend in skin cancer immunity. Cancer Cell , 43 (1) pp. 6-7. 10.1016/j.ccell.2024.12.005.

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Abstract

In this issue of Cancer Cell, Son et al. highlight an unexpected role for skin β-papillomaviruses in the protection against skin carcinogenesis. T cell immunity to skin papillomaviruses blocks the expansion of p53 mutant clones in ultraviolet (UV) radiation-damaged skin, preventing the development of skin cancer.

Type:	Article
Title:	Beta papillomaviruses: From foe to friend in skin cancer immunity
Location:	United States
DOI:	10.1016/j.ccell.2024.12.005
Publisher version:	https://doi.org/10.1016/j.ccell.2024.12.005
Language:	English
Additional information:	This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords:	Science & Technology, Life Sciences & Biomedicine, Oncology, Cell Biology, SQUAMOUS-CELL CARCINOMA
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
URI:	https://discovery.ucl.ac.uk/id/eprint/10206164

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