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Acute and chronic neuropathies

Ginsberg, L; (2020) Acute and chronic neuropathies. Medicine , 48 (9) pp. 612-618. 10.1016/j.mpmed.2020.06.009. Green open access

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Abstract

Peripheral nerve disorders are common and often treatable. The ‘default’ presentation of a polyneuropathy is a chronic, length-dependent, sensorimotor axonopathy. Recognizing deviations from this default, informed by the clinical features and investigations, can help identify the cause of a neuropathy in most cases. For inflammatory causes, such as Guillain–Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy, there are effective immunomodulatory treatments. For other neuropathies, management consists of supportive care and treatment of the underlying cause, to prevent or limit progression.

Type: Article
Title: Acute and chronic neuropathies
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mpmed.2020.06.009
Publisher version: https://doi.org/10.1016/j.mpmed.2020.06.009
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Carpal tunnel syndrome, Charcot–Marie–Tooth disease, chronic inflammatory demyelinating polyradiculoneuropathy, diabetes mellitus, Guillain–Barré syndrome, mononeuropathy, multifocal motor neuropathy, nerve biopsy, polyneuropathy, vasculitis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: https://discovery.ucl.ac.uk/id/eprint/10204035
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