Angeli, D;
Kelmali, E;
Kimiskidis, VK;
Bamiou, DE;
Maria Iliadou, V;
(2024)
Auditory processing in patients with temporal lobe epilepsy: A systematic review and meta-analysis.
Epilepsy and Behavior
, 160
, Article 110069. 10.1016/j.yebeh.2024.110069.
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Abstract
Background: Hearing efficiency is known to influence and interact with communication and mental health. Hearing impairment may be hidden when co-occurring with neurological disorders. Purpose: We performed a systematic review and meta-analysis in order to address the following questions: 1) which specific tools of auditory processing show clear deficits, separating Temporal Lobe Epilepsy (TLE) patients from normal controls,2) How well is TLE evaluated in terms of hearing and auditory processing? Methods: The study inclusion criteria were: 1) patients diagnosed with temporal lobe epilepsy, 2) presence of a normal control group, 3) auditory processing assessment using auditory stimuli with behavioral tests and/or P300 or Mitch Match Negativity (MMN) latency and/or amplitude, 4) publications written in English, 5) publication date after 2000. 132 articles were retrieved and based on PRISMA & PICO criteria 23 articles were analyzed. Results: Temporal resolution and processing as measured by the behavioral tests of Gaps-In-Noise (GIN) and Duration Pattern Test (DPT) document deficiencies in TLE patients and separate them from normal controls. Electrophysiology as measured by MMN & P300 shows statistically significant differences in TLE patients compared to controls with patients showing deficient auditory processing. A clear difference between studies with psychoacoustic assessment as opposed to electrophysiology ones may be due to lacking or incomplete evaluation of peripheral hearing by gold standard tools (76.9% in electrophysiology studies). Conclusion: Auditory processing is deficient in patients with TLE. There is a clear need to evaluate hearing efficiency before proceeding to auditory processing evaluation with behavioral or electrophysiological tests.
| Type: | Article |
|---|---|
| Title: | Auditory processing in patients with temporal lobe epilepsy: A systematic review and meta-analysis |
| Location: | United States |
| DOI: | 10.1016/j.yebeh.2024.110069 |
| Publisher version: | http://dx.doi.org/10.1016/j.yebeh.2024.110069 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Auditory processing, Duration pattern recognition, Hearing, Temporal lobe epilepsy, Time resolution, Humans, Acoustic Stimulation, Auditory Perception, Auditory Perceptual Disorders, Epilepsy, Temporal Lobe, Evoked Potentials, Auditory |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > The Ear Institute |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10200659 |
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