Pezzoli, Patrizia; McCrory, Eamon J; Viding, Essi; (2025) Shedding Light on Antisocial Behavior Through Genetically Informed Research. Annual Review of Psychology , 76 (27) pp. 1-23. 10.1146/annurev-psych-021524-043650.

Text Pezzoli_Shedding Light on Antisocial Behavior Through Genetically Informed Research_AAM.pdf - Accepted Version Access restricted to UCL open access staff until 24 October 2025. Download (635kB)

Abstract

Antisocial behavior (ASB) refers to a set of behaviors that violate social norms and disregard the well-being and rights of others. In this review, we synthesize evidence from studies using genetically informed designs to investigate the genetic and environmental contributions to individual differences in ASB. We review evidence from studies using family data (twin and adoption studies) and measured DNA (candidate gene and genome-wide association studies) that have informed our understanding of ASB. We describe how genetically informative designs are especially suited to investigate the nature of environmental risk and the forms of gene-environment interplay. We also highlight clinical and legal implications, including how insights from genetically informed research can help inform prevention and intervention, and we discuss some challenges and opportunities within this field of research.

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