Selten, JP;
Di Forti, M;
Quattrone, D;
Jones, PB;
Jongsma, HE;
Gayer-Anderson, C;
Szoeke, A;
... Termorshuizen, F; + view all
(2024)
The contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe.
Psychological Medicine
, 54
(11)
2937 -2946.
10.1017/S0033291724001004.
Preview |
Text
Kirkbride_the-contribution-of-cannabis-use-to-the-increased-psychosis-risk-among-minority-ethnic-groups-in-europe.pdf Download (192kB) | Preview |
Abstract
Background: We examined whether cannabis use contributes to the increased risk of psychotic disorder for non-western minorities in Europe. // Methods: We used data from the EU-GEI study (collected at sites in Spain, Italy, France, the United Kingdom, and the Netherlands) on 825 first-episode patients and 1026 controls. We estimated the odds ratio (OR) of psychotic disorder for several groups of migrants compared with the local reference population, without and with adjustment for measures of cannabis use. // Results: The OR of psychotic disorder for non-western minorities, adjusted for age, sex, and recruitment area, was 1.80 (95% CI 1.39–2.33). Further adjustment of this OR for frequency of cannabis use had a minimal effect: OR = 1.81 (95% CI 1.38–2.37). The same applied to adjustment for frequency of use of high-potency cannabis. Likewise, adjustments of ORs for most sub-groups of non-western countries had a minimal effect. There were two exceptions. For the Black Caribbean group in London, after adjustment for frequency of use of high-potency cannabis the OR decreased from 2.45 (95% CI 1.25–4.79) to 1.61 (95% CI 0.74–3.51). Similarly, the OR for Surinamese and Dutch Antillean individuals in Amsterdam decreased after adjustment for daily use: from 2.57 (95% CI 1.07–6.15) to 1.67 (95% CI 0.62–4.53). // Conclusions: The contribution of cannabis use to the excess risk of psychotic disorder for non-western minorities was small. However, some evidence of an effect was found for people of Black Caribbean heritage in London and for those of Surinamese and Dutch Antillean heritage in Amsterdam.
Type: | Article |
---|---|
Title: | The contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1017/S0033291724001004 |
Publisher version: | http://dx.doi.org/10.1017/s0033291724001004 |
Language: | English |
Additional information: | Copyright © The Author(s), 2024. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. |
Keywords: | Aetiology; Africa; amphetamine; cannabis; Caribbean; cocaine; ethnicity; migration; pathogenesis; psychotic disorder; schizophrenia; Surinam |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Epidemiology and Applied Clinical Research |
URI: | https://discovery.ucl.ac.uk/id/eprint/10198902 |
Archive Staff Only
![]() |
View Item |