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Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review

Habibollahi, Maryam; Jiang, Dai; Lancashire, Henry Thomas; Demosthenous, Andreas; (2024) Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review. IEEE Transactions on Biomedical Circuits and Systems , 18 (5) pp. 954-975. 10.1109/TBCAS.2024.3430038. Green open access

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Abstract

Interfaces with peripheral nerves have been widely developed to enable bioelectronic control of neural activity. Peripheral nerve neuromodulation shows great potential in addressing motor dysfunctions, neurological disorders, and psychiatric conditions. The integration of high-density neural electrodes with stimulation and recording circuits poses a challenge in the design of neural interfaces. Recent advances in active electrode strategies have achieved improved reliability and performance by implementing in-situ control, stimulation, and recording of neural fibers. This paper presents an overview of state-of-the-art neural interface systems that comprise a range of neural electrodes, neurostimulators, and bio-amplifier circuits, with a special focus on interfaces for the peripheral nerves. A discussion on the efficacy of active electrode systems and recommendations for future directions conclude this paper.

Type: Article
Title: Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/TBCAS.2024.3430038
Publisher version: http://dx.doi.org/10.1109/tbcas.2024.3430038
Language: English
Additional information: Copyright © 2024 The Authors. This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/.
Keywords: Active electrodes, biomedical electronics, integrated circuits, multi-electrode array, neural recording, neural stimulation, peripheral nerve interface
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10197862
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