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Pigmented clear cell sarcoma of soft tissue: an important diagnostic mimic

De Noon, Solange; Mendes, Bernardo Souza; Flanagan, Adrienne M; (2022) Pigmented clear cell sarcoma of soft tissue: an important diagnostic mimic. Diagnostic Histopathology , 28 (12) pp. 552-554. 10.1016/j.mpdhp.2022.09.005. Green open access

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Abstract

Clear cell sarcoma of soft tissue (CCSST) is a rare and aggressive soft tissue tumour associated with tendons and aponeuroses of the lower extremities. Due to its melanocytic differentiation, distinguishing CCSST from melanocytic neoplasms and other pigmented lesions can be challenging. We report a peculiar case of CCSST and discuss the histological, immunohistochemical and molecular features which can aid in accurate diagnosis of this entity.

Type: Article
Title: Pigmented clear cell sarcoma of soft tissue: an important diagnostic mimic
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mpdhp.2022.09.005
Publisher version: http://dx.doi.org/10.1016/j.mpdhp.2022.09.005
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Clear cell sarcoma; differential diagnosis; EWSR1; melanocytic
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Pathology
URI: https://discovery.ucl.ac.uk/id/eprint/10196513
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