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C3 glomerulopathy: consensus report

Pickering, Matthew C; D'Agati, Vivette D; Nester, Carla M; Smith, Richard J; Haas, Mark; Appel, Gerald B; Alpers, Charles E; ... Cook, H Terence; + view all (2013) C3 glomerulopathy: consensus report. Kidney International , 84 (6) pp. 1079-1089. 10.1038/ki.2013.377. Green open access

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Abstract

C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group.Kidney International advance online publication, 30 October 2013; doi:10.1038/ki.2013.377.

Type: Article
Title: C3 glomerulopathy: consensus report
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/ki.2013.377
Publisher version: http://dx.doi.org/10.1038/ki.2013.377
Language: English
Additional information: This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http:// creativecommons.org/licenses/by-nc-nd/3.0/
Keywords: Science & Technology, Life Sciences & Biomedicine, Urology & Nephrology, clinical immunology, clinical nephrology, complement, glomerulonephritis, immunology and pathology, DENSE-DEPOSIT DISEASE, COMPLEMENT FACTOR-H, MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS, PROVIDES INSIGHTS, ECULIZUMAB, MUTATION, CLASSIFICATION, DYSREGULATION, ACTIVATION, MECHANISM
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Renal Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10196197
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