Cipiccia, Silvia;
Fratini, Michela;
Erin, Ecem;
Palombo, Marco;
Vogel, Silvia;
Burian, Max;
Zhou, Fenglei;
... Batey, Darren J; + view all
(2024)
Fast X-ray ptychography: towards nanoscale imaging of large volume of brain.
European Physical Journal Plus (EPJ Plus)
, 139
(5)
, Article 434. 10.1140/epjp/s13360-024-05224-w.
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Abstract
X-ray ptychography, a scanning coherent diffraction imaging technique, is one of the most used techniques at synchrotron facilities for high resolution imaging, with applications spanning from life science to nano-electronics. In the recent years there has been a great effort to make the technique faster to enable high throughput nanoscale imaging. Here we apply a fast ptychography scanning method to image in 3D 106μm3 of brain-like phantom at 3 kHz, in a 7 h acquisition with a resolution of 270 nm. We then present the latest advances in fast ptychography by showing 2D images acquired at 110 kHz by combining the fast-acquisition scheme with a high-acquisition rate prototype detector from DECTRIS Ltd. We finally review the experimental outcome and discuss the prospective use of fast ptychography schemes for the investigation of mm3 size samples of brain-like phantom, by extrapolating the current results to the high coherent flux scenario of diffraction limited storage rings.
| Type: | Article |
|---|---|
| Title: | Fast X-ray ptychography: towards nanoscale imaging of large volume of brain |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1140/epjp/s13360-024-05224-w |
| Publisher version: | http://dx.doi.org/10.1140/epjp/s13360-024-05224-w |
| Language: | English |
| Additional information: | Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| Keywords: | Science & Technology, Physical Sciences, Physics, Multidisciplinary, Physics, PHASE RETRIEVAL, ALGORITHM |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10195450 |
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