Francis, Michaela;
Zirra, Alexandra;
Haque, Tahrina;
Gallagher, David;
Budu, Caroline;
Lees, Andrew J;
Schrag, Anette;
... Simonet, Cristina; + view all
(2024)
Rapid Voluntary Blinking as a Clinical Marker of Parkinson's Disease.
Journal of Parkinson's Disease
, 14
(5)
pp. 993-997.
10.3233/JPD-240005.
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Abstract
Reduced spontaneous blinking is a recognized Parkinson's disease (PD) feature. In contrast, voluntary blinking has been less studied and might serve as a measurable marker of facial bradykinesia. We tested 31 PD patients and 31 controls. Participants were filmed during conversation and a rapid blinking task. Both tasks were videorecorded to count the number of blinks per second. PD patients had lower blink rates. Rapid blinking accurately discriminated between groups with 77% sensitivity and 71% specificity. To conclude, rapid blinking may be a simple and quantifiable task of facial bradykinesia.
| Type: | Article |
|---|---|
| Title: | Rapid Voluntary Blinking as a Clinical Marker of Parkinson's Disease |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3233/JPD-240005 |
| Publisher version: | http://dx.doi.org/10.3233/jpd-240005 |
| Language: | English |
| Additional information: | © 2024 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4.0). |
| Keywords: | Blinking, Parkinson’s disease, bradykinesia, hypomimia, Humans, Parkinson Disease, Blinking, Male, Female, Aged, Middle Aged, Hypokinesia |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10195390 |
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