Singh, Dave;
Han, MeiLan K;
Hawkins, Nathaniel M;
Hurst, John R;
Kocks, Janwillem WH;
Skolnik, Neil;
Stolz, Daiana;
... Gale, Chris P; + view all
(2024)
Implications of Cardiopulmonary Risk for the Management of COPD: A Narrative Review.
Advances in Therapy
10.1007/s12325-024-02855-4.
(In press).
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Abstract
Chronic obstructive pulmonary disease (COPD) constitutes a major global health burden and is the third leading cause of death worldwide. A high proportion of patients with COPD have cardiovascular disease, but there is also evidence that COPD is a risk factor for adverse outcomes in cardiovascular disease. Patients with COPD frequently die of respiratory and cardiovascular causes, yet the identification and management of cardiopulmonary risk remain suboptimal owing to limited awareness and clinical intervention. Acute exacerbations punctuate the progression of COPD in many patients, reducing lung function and increasing the risk of subsequent exacerbations and cardiovascular events that may lead to early death. This narrative review defines and summarises the principles of COPD-associated cardiopulmonary risk, and examines respiratory interventions currently available to modify this risk, as well as providing expert opinion on future approaches to addressing cardiopulmonary risk.
| Type: | Article |
|---|---|
| Title: | Implications of Cardiopulmonary Risk for the Management of COPD: A Narrative Review |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s12325-024-02855-4 |
| Publisher version: | http://dx.doi.org/10.1007/s12325-024-02855-4 |
| Language: | English |
| Additional information: | © 2024 Springer Nature. This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/). |
| Keywords: | Cardiopulmonary risk, Cardiovascular disease, Chronic obstructive pulmonary disease, Exacerbation, Inhaled therapy, Mortality |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Respiratory Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10191837 |
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