Rashidi, Narjes;
Tamaddon, Maryam;
Liu, Chaozong;
(2023)
Protein-Based Scaffolds for Musculoskeletal Tissue Repair and Regeneration.
In: Maia, FRA and Oliveira, JM and Reis, RL, (eds.)
Handbook of the Extracellular Matrix.
(pp. 1-34).
Springer: Cham, Switzerland.
Preview |
Text
Liu_Protein-Based Scaffolds for Musculoskeletal Tissue Repair and Regeneration_chapter_AAM.pdf Download (2MB) | Preview |
Abstract
The musculoskeletal system, a main structure of the human body, plays a crucial role in movement, safeguarding internal organs, supporting the production of blood cells (hematopoiesis), and maintaining postural stability. Damage or loss to the tissues of the musculoskeletal system impairs mobility and quality of life. Tissue engineering and regenerative medicine have significantly contributed to developing new therapeutic approaches for the treatment of musculoskeletal disorders. The use of protein-based biomaterials has been rapidly growing over the last decade. Proteins mimic the extracellular matrix and have enzymatic degradation with non-toxic degradation products. They have superior bioactivity that promotes cell interaction and stimulates desired biological functions. This chapter discusses MS injuries, diseases, clinical specifications with respect to the composition of the musculoskeletal system and their characteristics, clinical requirements for the protein-based biomaterials and their application in MS tissue engineering, as well as the most common techniques used for the fabrication of protein-based scaffolds.
Archive Staff Only
 |
View Item |
