Dymerska, Barbara;
Josephs, Oliver;
Callaghan, Martina;
(2022)
Characterising the impact of distortion correction in high-resolution 3D GRE R2* mapping at 7T.
Presented at: Joint Annual Meeting ISMRM-ESMRMB ISMRT 31st Annual Meeting, London, UK.
(In press).
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Abstract
R2*-mapping delivers quantitative information about tissue microstructure. We investigate the scale of image distortions in high-resolution, bipolar, multi-echo GRE acquisitions at 7T and their effects on R2*-mapping. We study reduction in variance by applying field map-based distortion correction while also considering the confounding effect of local smoothing. We show that for regions with signal displacement > 0.5 voxels the reduction in variance comes largely, not from smoothing, but from the appropriate repositioning of the tissue signal. Therefore, correcting distortions, also in sub-voxel regime, improves data consistency in bipolar GRE acquisitions, facilitating more robust R2*-mapping in high-resolution laminar studies for instance.
| Type: | Conference item (UNSPECIFIED) |
|---|---|
| Title: | Characterising the impact of distortion correction in high-resolution 3D GRE R2* mapping at 7T |
| Event: | Joint Annual Meeting ISMRM-ESMRMB ISMRT 31st Annual Meeting |
| Location: | London, UK |
| Dates: | 7 May 2022 - 12 May 2022 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.58530/2022/2696 |
| Publisher version: | DOI: https://doi.org/10.58530/2022/2696 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10190739 |
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