Nieto-Calvache, Albaro José; Palacios-Jaraquemada, Jose M; Hussein, Ahmed M; Jauniaux, Eric; Milani Coutinho, Conrado; Rijken, Marcus; (2024) Management of placenta accreta spectrum in low- and middle-income countries. Best Practice & Research Clinical Obstetrics & Gynaecology , 94 , Article 102475. 10.1016/j.bpobgyn.2024.102475.

Text Jauniaux_Management of PAS YBEOG-D-23-94[16724] accepted version.pdf Access restricted to UCL open access staff until 8 March 2025. Download (1MB)

Abstract

Placenta accreta spectrum (PAS) can be associated massive intra- and post-operative hemorrhage which when not controlled can lead to maternal death. Important advances have occurred in understanding the pathophysiology and therapeutic options for this condition. The prevalence of PAS at birth is direct association with the cesarean delivery (CD) rate in the corresponding population and is increasing worldwide. Limited health infrastructure in low- and middle-income countries increases the morbidity and mortality of patients with PAS at birth. In many cases, obstetricians working in limited resources settings cannot follow some of the international guideline’s recommendations and have to opt for low-cost management procedures. In this review, we describe the particularities of managing PAS care in low- and middle-income countries from of prenatal evaluation of patients at risk of PAS at birth, therapeutic options, and inter-institutional collaboration. We also propose a management protocol based on training of the local obstetric teams rather than on sophisticated technological resources that are almost never available in low-resource scenarios.

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