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First Simultaneous Acquisition of a Clinical SPECT-MRI Brain INSERT

Morahan, Ashley J; D'Adda, Ilenia; Erlandsson, Kjell; Carminati, Marco; Rega, Marilena; Walls, Darren; Fiorini, Carlo; (2024) First Simultaneous Acquisition of a Clinical SPECT-MRI Brain INSERT. In: 2022 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). (pp. pp. 1-3). IEEE: Milan, Italy. Green open access

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Abstract

The INSERT (INtegrated SPECT/MRI for Enhanced stratification of brain tumours in Radio-chemoTherapy) is currently the only MRI-compatible SPECT stationary system for clinical application, in particular for brain multimodal imaging with an inner bore of 28 cm and a field of view of 20 cm (transaxial) × 10 cm (axial). The intrinsic spatial resolution is 1 mm and the extrinsic one is 10 mm. This modular scanner fits in an unmodified MRI scanner and is a scale-up of a smaller preclinical version, whose mutual compatibility with MRI was extensively characterized. It is composed of 20 detection modules (with 8-mm thick CsI:Tl scintillators of 5 cm 10 cm area read by an array of SiPM) and a massive multi-mini×slit-slat collimator, realized in tungsten. Here we report the first demonstration of successful simultaneous SPECT/MRI acquisition of phantoms (hot rods) using a commercial transceiver coil in a Siemens Biograph mMR scanner.

Type: Proceedings paper
Title: First Simultaneous Acquisition of a Clinical SPECT-MRI Brain INSERT
Event: 2022 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector (RTSD) Conference
Dates: 5 Nov 2022 - 12 Nov 2022
ISBN-13: 978-1-6654-8872-3
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/NSS/MIC44845.2022.10399278
Publisher version: http://dx.doi.org/10.1109/nss/mic44845.2022.103992...
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Coils; Scintillators; Magnetic resonance imaging; Energy resolution; Tungsten; Spatial resolution; Single photon emission computed tomography
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI: https://discovery.ucl.ac.uk/id/eprint/10189496
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