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Racioethnic Disparities in Endometrial Cancer Outcomes

Illah, Ojone; Adeeko, Deborah; Olaitan, Adeola; Gentry-Maharaj, Aleksandra; (2024) Racioethnic Disparities in Endometrial Cancer Outcomes. Diagnostics , 14 (4) , Article 417. 10.3390/diagnostics14040417. Green open access

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Abstract

Black women are twice as likely to die from endometrial cancer (EC) compared with white women. This represents one of the worst racioethnic disparities amongst all cancers globally. Compared with white women, black women are more likely to be diagnosed with advanced EC, have more barriers to accessing care and experience increased delays in obtaining an EC diagnosis and commencing treatment. Histological and molecular differences place black women at higher risk of being diagnosed with more aggressive EC subtypes that carry less favourable outcomes. Furthermore, EC diagnostic pathways are less reliable in black women, and black women are less likely to receive evidence-based treatment for EC. This racioethnic disparity in EC outcomes exists both in the UK and US, despite differences in healthcare systems. This review methodically describes the key factors along the patient journey that contribute to the disparity in black women and proposes multifaceted approaches to lessen these gaps.

Type: Article
Title: Racioethnic Disparities in Endometrial Cancer Outcomes
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/diagnostics14040417
Publisher version: http://dx.doi.org/10.3390/diagnostics14040417
Language: English
Additional information: Copyright © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Keywords: Endometrial cancer; endometrial cancer disparities; racial disparities; black women
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10188986
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