Michielin, Federica;
Urbani, Luca;
Luni, Camilla;
Gagliano, Onelia;
(2024)
Editorial: 3D-engineered organoids for modelling tissue development and precision medicine.
Frontiers in Chemical Engineering
, 6
, Article 1376921. 10.3389/fceng.2024.1376921.
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Abstract
Organoids are small, self-organized three-dimensional (3D) tissue cultures that reproduce organ structure and function, allowing to mimic physiological and pathological conditions and critical functions of organs. These features enable establishing a simplified, scalable, and accessible approach to address the human tissue availability constraints and the gap between animal models and patients. For this reason, organoid research has dramatically increased over the past decade, to create suitable microscale 3D tissue models that can be used for modelling human development, study disease pathophysiology and for personalized medicine.
| Type: | Article |
|---|---|
| Title: | Editorial: 3D-engineered organoids for modelling tissue development and precision medicine |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fceng.2024.1376921 |
| Publisher version: | http://dx.doi.org/10.3389/fceng.2024.1376921 |
| Language: | English |
| Additional information: | Copyright © 2024 Michielin, Urbani, Luni and Gagliano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Keywords: | Engineered organoids, 3D tissue modeling, microtechnologies, engineered scaffolds, stem cells |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10188971 |
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