Pipis, Menelaos;
Jaunmuktane, Zane;
Marafioti, Teresa;
Brandner, Sebastian;
Smith, Elaine C;
D'Sa, Shirley;
Lunn, Michael P;
... Reilly, Mary M; + view all
(2024)
Nerve biopsy in T-cell lymphoma with neurolymphomatosis: where and when.
Practical Neurology
10.1136/pn-2023-003992.
(In press).
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Abstract
Peripheral T-cell lymphomas are rare heterogeneous haematological malignancies that may also involve peripheral nerves in a very small subset of cases. We report a patient with a diagnostically challenging cutaneous T-cell lymphoma and multifocal mononeuropathies in whom a targeted nerve biopsy identified lymphomatous infiltration of nerves and expedited combination treatment with chemotherapy and an autologous stem cell transplant. She showed an excellent response with a complete metabolic response on positron emission tomography imaging and significant clinical improvement, maintained 5 years post-treatment.
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