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Making clinical trials a public norm for health decisions in sub-Saharan Africa

Agnandji, ST; Loembe, MM; Mbouna, AV; Mbadinga, F; Essone, PN; Mombo-Ngoma, G; Leke, R; ... Ntoumi, F; + view all (2023) Making clinical trials a public norm for health decisions in sub-Saharan Africa. Frontiers in Tropical Diseases , 4 , Article 1297109. 10.3389/fitd.2023.1297109. Green open access

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Abstract

A clinical trial is intrinsically a collaborative undertaking. The complex steps, including identifying the biological mechanisms, discovering products, preclinical studies, and the clinical development from phase 1 to 3 clinical trials allowing market authorisation of a product, are unlikely to be feasible for a single institution or a country alone. Collaboration is therefore necessary to establish and maintain the research and innovation that is a prerequisite to tackle health threats, irrespective of the socioeconomic status of the countries (1).

Type: Article
Title: Making clinical trials a public norm for health decisions in sub-Saharan Africa
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fitd.2023.1297109
Publisher version: http://dx.doi.org/10.3389/fitd.2023.1297109
Language: English
Additional information: Copyright © 2024 Agnandji, Loembe, Mbouna, Mbadinga, Essone, Mombo-Ngoma, Leke, Mburu, Muyembe-Tamfum, Okwo-Bele, Sow, Wiysonge, Zumla, Adegnika, Ramharter, Kremsner, Matsiegui, Boum and Ntoumi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: Clinical trial as a public norm, sub-Saharan Africa, evidence-based decision-making in public health, clinical trial literacy, clinical trial law, international collaborations
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/10187508
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