Georgiou, Michalis;
Shakarchi, Ahmed F;
Elhusseiny, Abdelrahman M;
Michaelides, Michel;
Sallam, Ahmed B;
(2024)
Cataract Surgery Outcomes in Retinitis Pigmentosa A Comparative Clinical Database Study.
American Journal of Ophthalmology
, 262
pp. 34-39.
10.1016/j.ajo.2024.01.037.
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Abstract
PURPOSE: To report visual acuity (VA) outcomes, intraoperative and postoperative complications of isolated cataract surgery in eyes with retinitis pigmentosa (RP), compared with non-RP-affected eyes. DESIGN: Retrospective clinical cohort study. METHODS: A total of 113,389 eyes underwent cataract surgery between December 2010 and December 2014 at 8 clinical sites in the United Kingdom. Eyes with RP as the only comorbid pathology and eyes without any ocular comorbidities (controls) undergoing cataract surgery were compared. VA at 4-12 weeks postoperatively and rates of intraoperative and postoperative complications are reported. RESULTS: Seventy-two eyes had RP. The mean age in the RP group was 57±15 compared to 75±10 in controls (p<0.001). Females represented 46% of RP cases and 60% of controls (p=0.06). Preoperative VA (mean LogMAR = 1.03 vs 0.59, p<0.001) and postoperative VA (0.71 vs 0.14, p<0.001) were worse in RP. The mean VA gain was 0.25±0.60 LogMAR in RP vs 0.43±0.48 LogMAR in controls (p<0.001). There were no significant differences in the rate of intraoperative pupil expansion use, posterior capsular tears, or zonular dialysis. Postoperative cystoid macular edema developed in 6.9% of RP eyes and 1% of controls (p<0.001). The need for IOL repositioning or exchange was not statistically different between the two groups. CONCLUSION: Cataract surgery can improve vision in eyes with RP and cataract. Intraoperative complications were similar to control eyes; however, RP eyes experienced more frequent postoperative cystoid macular edema.
Type: | Article |
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Title: | Cataract Surgery Outcomes in Retinitis Pigmentosa A Comparative Clinical Database Study |
Location: | United States |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1016/j.ajo.2024.01.037 |
Publisher version: | http://dx.doi.org/10.1016/j.ajo.2024.01.037 |
Language: | English |
Additional information: | Copyright © 2024 The Authors. This is an open access article under the CC BY licence (https://creativecommons.org/licenses/by/4.0/). |
Keywords: | RP, cataract, complications zonular dialysis, cystoid macular edema, retinal dystrophy, retinitis pigmentosa |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
URI: | https://discovery.ucl.ac.uk/id/eprint/10186833 |
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