Brown, Michael D;
Generowicz, Bastian S;
Dijkhuizen, Stephanie;
Koekkoek, Sebastiaan KE;
Strydis, Christos;
Bosch, Johannes G;
Arvanitis, Petros;
... Kruizinga, Pieter; + view all
(2024)
Four-dimensional computational ultrasound imaging of brain hemodynamics.
Science Advances
, 10
(3)
, Article eadk7957. 10.1126/sciadv.adk7957.
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Abstract
Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), an imaging method that uses complex ultrasound fields that can be generated with simple hardware and a physical wave prediction model to alleviate the sampling constraints. cUSi allows for high-resolution four-dimensional imaging of brain hemodynamics in awake and anesthetized mice.
| Type: | Article |
|---|---|
| Title: | Four-dimensional computational ultrasound imaging of brain hemodynamics |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1126/sciadv.adk7957 |
| Publisher version: | https://doi.org/10.1126/sciadv.adk7957 |
| Language: | English |
| Additional information: | Copyright © 2024 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Mice, Animals, Brain, Ultrasonography, Hemodynamics, Wakefulness |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10186159 |
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