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Acute pancreatitis

Ney, A; Pereira, SP; (2024) Acute pancreatitis. Medicine , 52 (2) pp. 99-107. 10.1016/j.mpmed.2023.11.005. Green open access

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Abstract

Acute pancreatitis is an inflammatory condition with a variable clinical course. Its diagnosis involves a combination of clinical assessment, laboratory tests and imaging studies. Disease severity can be determined using clinical scoring systems or radiological evaluations such as the Computed Tomography Severity Index. While most cases of acute pancreatitis have a mild course, a subset of patients experience complications at both local and systemic levels. Conservative management is typically employed, but interventions are warranted in the presence of common bile duct stones or local complications such as walled-off necrosis or pseudocyst formation. This review provides recent insights into the pathophysiology, diagnostic approaches and treatment strategies for acute pancreatitis, with a particular focus on the management of local complications.

Type: Article
Title: Acute pancreatitis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mpmed.2023.11.005
Publisher version: https://doi.org/10.1016/j.mpmed.2023.11.005
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Acute pancreatitis, antibiotics, endoscopic necrosectomy, MRCP, nutrition, pseudocyst, severity
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
URI: https://discovery.ucl.ac.uk/id/eprint/10186058
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