Allegrini, Davide;
Montesano, Giovanni;
Marconi, Stefania;
Rosso, Nicoletta;
Ometto, Giovanni;
Raimondi, Raffaele;
Auricchio, Ferdinando;
... Romano, Mario R; + view all
(2021)
A novel quantitative analysis method for idiopathic epiretinal membrane.
PLOS ONE
, 16
(3)
, Article e0247192. 10.1371/journal.pone.0247192.
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Abstract
Purpose To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. Methods Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery. Results Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline. Conclusion While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction. Copyright:
| Type: | Article |
|---|---|
| Title: | A novel quantitative analysis method for idiopathic epiretinal membrane |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pone.0247192 |
| Publisher version: | https://doi.org/10.1371/journal.pone.0247192 |
| Language: | English |
| Additional information: | Copyright: © 2021 Allegrini et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10183878 |
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