Othman, M;
Ariff, AB;
Rios-Solis, L;
Halim, M;
(2017)
Extractive fermentation of lactic acid in lactic acid bacteria cultivation: A review.
Frontiers in Microbiology
, 8
p. 2285.
10.3389/fmicb.2017.02285.
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Abstract
Lactic acid bacteria are industrially important microorganisms recognized for their fermentative ability mostly in their probiotic benefits as well as lactic acid production for various applications. Nevertheless, lactic acid fermentation often suffers end-product inhibition which decreases the cell growth rate. The inhibition of lactic acid is due to the solubility of the undissociated lactic acid within the cytoplasmic membrane and insolubility of dissociated lactate, which causes acidification of cytoplasm and failure of proton motive forces. This phenomenon influences the transmembrane pH gradient and decreases the amount of energy available for cell growth. In general, the restriction imposed by lactic acid on its fermentation can be avoided by extractive fermentation techniques, which can also be exploited for product recovery.
| Type: | Article |
|---|---|
| Title: | Extractive fermentation of lactic acid in lactic acid bacteria cultivation: A review |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fmicb.2017.02285 |
| Publisher version: | https://doi.org/10.3389/fmicb.2017.02285 |
| Language: | English |
| Additional information: | Copyright © 2017 Othman, Ariff, Rios-Solis and Halim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Keywords: | extractive fermentation, in situ removal, lactic acid, lactic acid bacteria, probiotic, product inhibition |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Biochemical Engineering |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10183116 |
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