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Trypanosoma cruzi screening in people living with HIV in the UK

Ahmed, N; Herbert, S; Arenas-Pinto, A; Rickman, H; Benn, P; Edwards, SG; Chiodini, PL; (2023) Trypanosoma cruzi screening in people living with HIV in the UK. International Journal of STD and AIDS 10.1177/09564624231202292. (In press). Green open access

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Abstract

People living with HIV (PLWH) are at higher risk of reactivation of Chagas disease, a neglected tropical disease, caused by Trypanosoma cruzi. There are no data from UK HIV clinics on the prevalence of T. cruzi. We implemented T. cruzi screening at our clinic as part of routine care for PLWH with epidemiological risk factors. Among 86 patients screened, none had positive serology: one seropositive patient was identified due to increased clinician awareness. Implementing T. cruzi screening as part of routine clinical care was feasible, though labour intensive and identified at-risk individuals.

Type: Article
Title: Trypanosoma cruzi screening in people living with HIV in the UK
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/09564624231202292
Publisher version: https://doi.org/10.1177/09564624231202292
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: HIV, Chagas disease, Trypanosoma cruzi, T.Cruzi, screening
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/10182547
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