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Studies and research design in medicine

Bulanov, NM; Blyuss, OB; Munblit, DB; Nekliudov, NA; Butnaru, DV; Kodzoeva, KB; Nadinskaia, M Yu; (2021) Studies and research design in medicine. Sechenov Medical Journal , 12 (1) pp. 4-17. 10.47093/2218-7332.2021.12.1.4-17. Green open access

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Abstract

Adequate design is an essential condition for conducting a successful study. This review describes the most common types of research design in medicine. We discuss the differences between different types of observational and interventional studies, their advantages and limitations providing examples for each study design. The concept of bias and its potential sources in different studies are covered. We suggest the most suitable approaches to study design for different research objectives and outline approaches to data presentation. During the last decades, several guidelines for conducting and reporting different types of research were proposed and they are also covered in this manuscript.

Type: Article
Title: Studies and research design in medicine
Open access status: An open access version is available from UCL Discovery
DOI: 10.47093/2218-7332.2021.12.1.4-17
Publisher version: https://doi.org/10.47093/2218-7332.2021.12.1.4-17
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/).
Keywords: Statistics, case report, cross-sectional studies, case-control studies, cohort studies, randomised controlled trials as Topic, meta-analysis as Topic, bias
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Womens Cancer
URI: https://discovery.ucl.ac.uk/id/eprint/10182248
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