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The BioPoly Partial Resurfacing Knee Implant Provides Beneficial Clinical Outcomes A Concise Follow-up, at 5 Years, of a Previous Report*

Nathwani, Dinesh; McNicholas, Michael; Hart, Alister; Miles, Jonathan; Bobić, Vladimir; (2023) The BioPoly Partial Resurfacing Knee Implant Provides Beneficial Clinical Outcomes A Concise Follow-up, at 5 Years, of a Previous Report*. JBJS Open Access , 8 (4) , Article e23.00008. 10.2106/JBJS.OA.23.00008. Green open access

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Abstract

We previously conducted a single-arm, prospective study in which 31 patients (mean age [and standard deviation], 42.5 ± 11.3 years) with cartilage lesions were treated with use of the BioPoly Partial Resurfacing Knee Implant. Treatment outcomes were compared with those reported for the standard of care, microfracture. We found that the mean KOOS (Knee injury and Osteoarthritis Outcome Score) Quality of Life score at 5 years in the BioPoly cohort was noninferior to (p = 0.004), and indeed greater than (p = 0.021), that in the microfracture cohort. The BioPoly cohort demonstrated improvement in the mean scores for all KOOS domains at every postoperative time point (p < 0.025). The mean score for the visual analog scale (VAS) for pain significantly improved (p < 0.025) at all time points up to 4 years and trended toward significant improvement at 5 years (p = 0.027). This study indicated that the BioPoly implant was safe, provided significant improvement starting at 6 months and continuing to 5 years, and provided greater improvement than microfracture for some outcome measures.

Type: Article
Title: The BioPoly Partial Resurfacing Knee Implant Provides Beneficial Clinical Outcomes A Concise Follow-up, at 5 Years, of a Previous Report*
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.2106/JBJS.OA.23.00008
Publisher version: https://doi.org/10.2106/JBJS.OA.23.00008
Language: English
Additional information: Copyright © 2023 The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated. All rights reserved. This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CC-BY-NC-ND), https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
URI: https://discovery.ucl.ac.uk/id/eprint/10181407
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