UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations

Yu, RC; Lai, JC; Hui, EK; Mukadam, N; Kapur, N; Stott, J; Livingston, G; (2023) Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations. Journal of Alzheimer's Disease Reports , 7 (1) pp. 973-987. 10.3233/ADR-230024. Green open access

[thumbnail of adr_2023_7-1_adr-7-1-adr230024_adr-7-adr230024.pdf]
Preview
Text
adr_2023_7-1_adr-7-1-adr230024_adr-7-adr230024.pdf - Published Version

Download (2MB) | Preview

Abstract

Background: Chinese is the most commonly spoken world language; however, most cognitive tests were developed and validated in the West. It is essential to find out which tests are valid and practical in Chinese speaking people with suspected dementia. Objective: We therefore conducted a systematic review and meta-Analysis of brief cognitive tests adapted for Chinese-speaking populations in people presenting for assessment of suspected dementia. Methods: We searched electronic databases for studies reporting brief (≤20 minutes) cognitive test's sensitivity and specificity as part of dementia diagnosis for Chinese-speaking populations in clinical settings. We assessed quality using Centre for Evidence Based Medicine (CEBM) criteria and translation and cultural adaptation using the Manchester Translation Reporting Questionnaire (MTRQ), and Manchester Cultural Adaptation Reporting Questionnaire (MCAR). We assessed heterogeneity and combined sensitivity in meta-Analyses. Results: 38 studies met inclusion criteria and 22 were included in meta-Analyses. None met the highest CEBM criteria. Five studies met the highest criteria of MTRQ and MCAR. In meta-Analyses of studies with acceptable heterogeneity (I2 <  75%), Addenbrooke's Cognitive Examination Revised III (ACE-R ACE-III) had the best sensitivity and specificity; specifically, for dementia (93.5% 85.6%) and mild cognitive impairment (81.4% 76.7%). Conclusions: Current evidence is that the ACE-R and ACE-III are the best brief cognitive assessments for dementia and mild cognitive impairment in Chinese-speaking populations. They may improve time taken to diagnosis, allowing people to access interventions and future planning.

Type: Article
Title: Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations
Open access status: An open access version is available from UCL Discovery
DOI: 10.3233/ADR-230024
Publisher version: http://dx.doi.org/10.3233/ADR-230024
Language: English
Additional information: © 2023 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4.0).
Keywords: Alzheimer’s disease, cognitive assessment, dementia, diagnosis, mild cognitive impairment
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People
URI: https://discovery.ucl.ac.uk/id/eprint/10177839
Downloads since deposit
Loading...
0Downloads
Download activity - last month
Loading...
Download activity - last 12 months
Loading...
Downloads by country - last 12 months
Loading...

Archive Staff Only

View Item View Item