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Do we know what causes endometriosis?

Wagstaff, Duncan; Becker, Christian M; (2008) Do we know what causes endometriosis? British Journal of Hospital Medicine , 69 (6) pp. 314-315. 10.12968/hmed.2008.69.6.29617. Green open access

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Abstract

Edometriosis is one of the most intensively investigated benign gynaecological disorders, but our understanding of its causation remains surprisingly incomplete. Several theories exist: coelomic metaplasia, induction, retrograde menstruation and implantation, Müllerian remnants and the archimetra concept. These hypotheses show various extents of plausibility and supporting scientific data. While the theory of retrograde menstruation and implantation is the most widely accepted, no single concept explains all forms and appearances of endometriosis. Indeed, the wide variety in incidence and progression of the disease seem to defy an explanation by a single mechanism which may indicate that endometriosis is a heterogenous disease. In addition, there is considerable overlap between most of the proposed theories

Type: Article
Title: Do we know what causes endometriosis?
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.12968/hmed.2008.69.6.29617
Publisher version: https://doi.org/10.12968/hmed.2008.69.6.29617
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/10177735
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