Azimbagirad, M;
Dardenne, G;
Salema, DB;
Rémy-Néris, O;
Burdin, V;
(2021)
Combined multi-protocols qMRI for thigh muscle analysis: a preliminary study.
In:
Proceedings Volume 12088, 17th International Symposium on Medical Information Processing and Analysis; 120880G.
SPIE: Campinas, Brazil.
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Abstract
Quantitative MRI (qMRI) has been shown to be crucial for assessing organ dysfunction in the body. Usually, in qMRI approaches, a few metrics are extracted to distinguish normal and abnormal tissues. In this study, we coupled four MRI protocols (mDIXON T1, T1 and T2 mapping and DTI) to obtain 34 complementary metrics including 20 shape metrics, 2 texture metrics and 12 water diffusivity metrics for thigh muscle analysis. These metrics were calculated on both thighs to detect a pathological difference between a pair of right and left muscles. The method is based on a dimension reduction method and a projection of shape and diffusivity metrics into a three-dimensional linear latent space, along with two texture metrics. 5 healthy individuals (10 thighs, each thigh 7 muscles, i.e., 4 exors and 3 extensors) were scanned to provide the reference scores. The developed pipeline was used to analyse the pair thighs of 4 patients in order to suggest a specific muscle therapy before total knee arthroplasty (TKA) individually for each of the 7 muscles. Preliminary results from the analysis of thigh muscle texture, shape and diffusivity showed that this qMRI protocol can help to suggest a targeted, patient-specific exercise plan to improve muscle recovery after TKA surgery. More healthy and pathological subjects are needed to confirm these encouraging results.
| Type: | Proceedings paper |
|---|---|
| Title: | Combined multi-protocols qMRI for thigh muscle analysis: a preliminary study |
| Event: | Seventeenth International Symposium on Medical Information Processing and Analysis, 2021 |
| Dates: | 17 Nov 2021 - 19 Nov 2021 |
| ISBN-13: | 9781510650527 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/12.2604236 |
| Publisher version: | https://doi.org/10.1117/12.2604236 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | qMRI, thigh muscles analysis, Principal Component Analysis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10177536 |
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