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Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy

Beck, AJ; Reddy, VM; Sulkin, T; Browne, D; (2022) Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy. Endocrinology, Diabetes and Metabolism Case Reports , 2022 (1) pp. 1-4. 10.1530/EDM-21-0203. Green open access

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Abstract

Primary hyperparathyroidism (PHP) is the most common aetiology for hypercalcaemia. The incidence of PHP in pregnant women is reported to be 8/100 000 population/year. It presents a threat to the health of both mother (hyperemesis, nephrolithiasis) and fetus (fetal death, congenital malformations, and neonatal severe hypocalcaemia-induced tetany). However, there is a lack of clear guidance on the management of primary hyperparathyroidism in pregnancy. In this study, we describe the case of a 26-year-old female patient who presented with severe hypercalcaemia secondary to PHP and underwent successful parathyroid adenectomy under local anaesthesia.

Type: Article
Title: Management of severe and symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy
Open access status: An open access version is available from UCL Discovery
DOI: 10.1530/EDM-21-0203
Publisher version: https://doi.org/10.1530/EDM-21-0203
Language: English
Additional information: This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. See: https://creativecommons.org/licenses/by-nc-nd/4.0/
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharma and Bio Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10176175
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