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Cell-matrix and cell-cell interaction mechanics in guiding migration

Le, Hoang Anh; Mayor, Roberto; (2023) Cell-matrix and cell-cell interaction mechanics in guiding migration. Biochemical Society Transactions , 51 (4) pp. 1733-1745. 10.1042/BST20230211. Green open access

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Abstract

Physical properties of tissue are increasingly recognised as major regulatory cues affecting cell behaviours, particularly cell migration. While these properties of the extracellular matrix have been extensively discussed, the contribution from the cellular components that make up the tissue are still poorly appreciated. In this mini-review, we will discuss two major physical components: stiffness and topology with a stronger focus on cell-cell interactions and how these can impact cell migration.

Type: Article
Title: Cell-matrix and cell-cell interaction mechanics in guiding migration
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1042/BST20230211
Publisher version: https://doi.org/10.1042/BST20230211
Language: English
Additional information: © 2023 The Author(s). This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (https://creativecommons.org/licenses/by/4.0/).
Keywords: cell migration, cell–cell interactions, mechanobiology, stiffness, tissue mechanics
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: https://discovery.ucl.ac.uk/id/eprint/10175933
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