UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Rhegmatogenous retinal detachment in choroidal melanoma: clinical features and surgical outcomes

Anguita, Rodrigo; Makuloluwa, Achini; Bhalla, Minak; Katta, Mohamed; Sagoo, Mandeep S; Charteris, David G; (2024) Rhegmatogenous retinal detachment in choroidal melanoma: clinical features and surgical outcomes. Eye , 38 pp. 494-498. 10.1038/s41433-023-02709-3. Green open access

[thumbnail of RHEGMATOGENOUS RETINAL DETACHMENT IN CHOROIDAL MELANOMA- CLINICAL FEATURES AND SURGICAL OUTCOMES .pdf]
Preview
Text
RHEGMATOGENOUS RETINAL DETACHMENT IN CHOROIDAL MELANOMA- CLINICAL FEATURES AND SURGICAL OUTCOMES .pdf - Accepted Version

Download (621kB) | Preview

Abstract

Purpose: To describe the clinical features, prognostic factors, safety and rate of success of surgery and visual outcomes in patients with rhegmatogenous retinal detachment (RRD) and choroidal melanoma (CM).// Methods: A retrospective, observational case-series of 21 patients with rhegmatogenous retinal detachment or combined tractional-rhegmatogenous retinal detachment in patients with choroidal melanoma over a period of 20 years.// Results: Nineteen patients were included in the final analysis. The mean elevation of CM was 4.0 mm and the mean largest diameter was 11.0 mm. RRD occurred after the CM treatment in 14 eyes at a mean interval of 44.2 months. The RRD was macula-on RRD in 6 eyes, there was posterior vitreous detachment (PVD) in 15 and PVR in 7 eyes. BCVA at presentation was 0.71 logMAR and final was 1.5 logMAR (p = 0.01). The primary surgical success rate was 59%. No intraocular or extraocular tumour dissemination occurred. Mean follow-up was 66 months.// Conclusion: RRD in patients with CM is uncommon but requires multidisciplinary management. Anatomical results are favourable but visual outcomes are poor due to a combination of factors related to melanoma treatment, macular retinal detachment and PVR. Vitrectomy as a surgical intervention for RRD in treated CM appears to be safe in terms tumour dissemination.

Type: Article
Title: Rhegmatogenous retinal detachment in choroidal melanoma: clinical features and surgical outcomes
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41433-023-02709-3
Publisher version: https://doi.org/10.1038/s41433-023-02709-3
Language: English
Additional information: This version is the author-accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Eye cancer, Outcomes research
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10175594
Downloads since deposit
10Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item