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Literature review of the mechanisms of acute kidney injury secondary to acute liver injury

Platt, E; Klootwijk, E; Salama, A; Davidson, B; Robertson, F; (2022) Literature review of the mechanisms of acute kidney injury secondary to acute liver injury. World Journal of Nephrology , 11 (1) pp. 13-29. 10.5527/wjn.v11.i1.13. Green open access

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Abstract

People exposed to liver ischaemia reperfusion (IR) injury often develop acute kidney injury and the combination is associated with significant morbidity and mortality. Molecular mediators released by the liver in response to IR injury are the likely cause of acute kidney injury (AKI) in this setting, but the mediators have not yet been identified. Identifying the mechanism of injury will allow the identification of therapeutic targets which may modulate both liver IR injury and AKI following liver IR injury.

Type: Article
Title: Literature review of the mechanisms of acute kidney injury secondary to acute liver injury
Open access status: An open access version is available from UCL Discovery
DOI: 10.5527/wjn.v11.i1.13
Publisher version: http://dx.doi.org/10.5527/wjn.v11.i1.13
Language: English
Additional information: © 2023 Baishideng Publishing Group Inc. This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license (https://creativecommons.org/licenses/by-nc/4.0/).
Keywords: Liver failure; Liver transplantation; Ischaemia-reperfusion injury; Acute kidney injury; Liver
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Renal Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/10173812
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