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Older and wiser: The benefits to neonates of aged neutrophils

B. Collins, G; Gilroy, D; (2023) Older and wiser: The benefits to neonates of aged neutrophils. Immunity , 56 (6) pp. 1157-1159. 10.1016/j.immuni.2023.05.012.

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Abstract

Neonates are relatively protected from non-neonatal pathogens by unclear mechanisms. In this issue of Immunity, Bee et al.1 show that resistance to Streptococcus pneumoniae in neonatal mice is mediated by dampened neutrophil efferocytosis, accumulation of aged neutrophils, and enhanced CD11b-dependent bacterial opsonophagocytosis.

Type: Article
Title: Older and wiser: The benefits to neonates of aged neutrophils
Location: United States
DOI: 10.1016/j.immuni.2023.05.012
Publisher version: https://doi.org/10.1016/j.immuni.2023.05.012
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Animals, Bees, Mice, Neutrophils, Phagocytosis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10172855
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