PINK1: From Parkinson's disease to mitophagy and back again

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PINK1: From Parkinson's disease to mitophagy and back again

O'Callaghan, Benjamin; Hardy, John; Plun-Favreau, Helene; (2023) PINK1: From Parkinson's disease to mitophagy and back again. PLoS Biology , 21 (6) , Article e3002196. 10.1371/journal.pbio.3002196. Green open access

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Abstract

The genetics of Parkinson's disease has been key to unravelling the PINK1-dependent mitophagy process. Here, we discuss the implications of a 2010 PLOS Biology paper that shed light on the functional importance of PINK1 in the mitophagy cascade.

Type:	Article
Title:	PINK1: From Parkinson's disease to mitophagy and back again
Location:	United States
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1371/journal.pbio.3002196
Publisher version:	https://doi.org/10.1371/journal.pbio.3002196
Language:	English
Additional information:	© 2023 O’Callaghan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
URI:	https://discovery.ucl.ac.uk/id/eprint/10172812

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