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Edge-Illumination X-Ray Dark-Field Tomography

Doherty, A; Savvidis, S; Navarrete-León, C; Olivo, A; Endrizzi, M; Gerli, MFM; (2023) Edge-Illumination X-Ray Dark-Field Tomography. Physical Review Applied , 19 (5) , Article 054042. 10.1103/PhysRevApplied.19.054042. Green open access

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Abstract

Dark-field imaging is an x-ray technique used to highlight subpixel, typically micrometer-scale, density fluctuations. It is often used alongside standard attenuation-based and also phase-contrast x-ray imaging, which both see regular use in tomography. We present x-ray dark-field computed tomography (CT) with a laboratory edge-illumination setup. The dark-field contrast is shown to increase linearly with the x-ray path length through the imaged object, a prerequisite for the use of standard tomographic reconstruction approaches. A multimaterial, custom-built phantom is used to show how dark-field contrast CT can complement attenuation contrast CT for the separation of materials based on their microstructure. As an example of a more complex, biological sample, we present a model rat heart. We show, by comparison with attenuation contrast tomography, that dark-field enables the identification of additional structures undetected through the attenuation contrast channel, as well as offering a consistently sharper reconstructed image.

Type: Article
Title: Edge-Illumination X-Ray Dark-Field Tomography
Open access status: An open access version is available from UCL Discovery
DOI: 10.1103/PhysRevApplied.19.054042
Publisher version: https://doi.org/10.1103/PhysRevApplied.19.054042
Language: English
Additional information: © 2023 American Physical Society. Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10170589
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