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Epitheloid Angiomyolipomas of the Kidney: Rare Renal Tumors Associated With Poor Prognoses

Aquilina, J; Neves, JB; El-Sheikh, S; Tran-Dang, MA; Walkden, M; Barod, R; Patki, P; ... Tran, MGB; + view all (2023) Epitheloid Angiomyolipomas of the Kidney: Rare Renal Tumors Associated With Poor Prognoses. Urology , 176 pp. 102-105. 10.1016/j.urology.2023.03.017. Green open access

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Abstract

Objective: To demonstrate the clinical spectrum and challenges associated with clinical management of epitheloid angiomyolipomas (eAML). Methods: We retrospectively reviewed the surgical database of a high-volume tertiary kidney cancer center from 2015 to 2020 to identify cases with a final histological diagnosis of eAML. Descriptive analysis of all cases was conducted. Results: Five surgical cases of eAMLs were identified. Two of which have had no tumor recurrence since surgery, and three patients passed away due to disease progression. Conclusion: eAML are rare renal tumors which the World Health Organisation (5th Edition, 2022) and International Classification of Diseases for Oncology classify as having unspecified, borderline, or uncertain behavior. Here, we report that can also demonstrate aggressive behavior with fatal consequences. Post-operative follow-up should be recommended for all, with shorter intervals for patients with poor prognostic factors.

Type: Article
Title: Epitheloid Angiomyolipomas of the Kidney: Rare Renal Tumors Associated With Poor Prognoses
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.urology.2023.03.017
Publisher version: https://doi.org/10.1016/j.urology.2023.03.017
Language: English
Additional information: © 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/10169868
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