Latorre, Sergio M;
Were, Vincent M;
Foster, Andrew J;
Langner, Thorsten;
Malmgren, Angus;
Harant, Adeline;
Asuke, Soichiro;
... Kamoun, Sophien; + view all
(2023)
Genomic surveillance uncovers a pandemic clonal lineage of the wheat blast fungus.
PLoS Biology
, 21
(4)
, Article e3002052. 10.1371/journal.pbio.3002052.
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Abstract
Wheat, one of the most important food crops, is threatened by a blast disease pandemic. Here, we show that a clonal lineage of the wheat blast fungus recently spread to Asia and Africa following two independent introductions from South America. Through a combination of genome analyses and laboratory experiments, we show that the decade-old blast pandemic lineage can be controlled by the Rmg8 disease resistance gene and is sensitive to strobilurin fungicides. However, we also highlight the potential of the pandemic clone to evolve fungicide-insensitive variants and sexually recombine with African lineages. This underscores the urgent need for genomic surveillance to track and mitigate the spread of wheat blast outside of South America and to guide preemptive wheat breeding for blast resistance.
| Type: | Article |
|---|---|
| Title: | Genomic surveillance uncovers a pandemic clonal lineage of the wheat blast fungus |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pbio.3002052 |
| Publisher version: | https://doi.org/10.1371/journal.pbio.3002052 |
| Language: | English |
| Additional information: | © 2023 Latorre et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10168773 |
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